Project title: MiRNAs as therapeutics for neurorepair in Multiple Sclerosis
Dr Claire McCoy at RCSI, Dr Una Fitzgerald at NUIG and Dr Yvonne Dombrowksi at QUB are scheduled to begin a project on 1 May 2021, entitled “MiRNAs as therapeutics for neurorepair in Multiple Sclerosis”. The work will be led by María Muñoz San Martín who was awarded a Marie Skłodowska-Curie Actions Individual Fellowship in the 2020 call. This heralds the first ‘offical joint project’ under the remit of the AIMS Research Network and promises to bring together lead scientists in Ireland to address a fundamental research question in the MS field.
The main aim of the project is to identify microRNAs involved in the damage and endogenous repair associated with MS by combining human miRNA data with robust experimental models. In addition, the modulation of selected miRNA expression will be studied as a therapeutic tool in conjunction with novel bioscaffolds to promote neurorepair in MS.